Table 4. Factors associated with adverse event emergence.
Factor | N | % | Adverse Event Emergence | p-value | ORa | 95%CI | p-value | |||
---|---|---|---|---|---|---|---|---|---|---|
N | Adverse Event Incidence, % | |||||||||
Overall b | 812 | 100.0 | 170 | 20.9 | ||||||
Patient Characteristic | ||||||||||
Sex | 0.090c | |||||||||
Male | 248 | 31.5 | 43 | 17.3 | ||||||
Female | 539 | 68.5 | 122 | 22.6 | ||||||
Age | 0.244d | |||||||||
Mean | 58 | 7.2 | 10 | 17.2 | ||||||
< 75 years | 117 | 14.6 | 24 | 20.5 | ||||||
≥ 75 and < 80 years | 227 | 28.3 | 44 | 19.4 | ||||||
≥ 80 and < 85 years | 235 | 29.3 | 51 | 21.7 | ||||||
≥ 85 and < 90 years | 164 | 20.5 | 39 | 23.8 | ||||||
Nursing care level | 0.052c | |||||||||
Independent/Assistance Required/Nursing Care Levels I-II | 454 | 58.7 | 87 | 19.2 | ||||||
Ⅲ - Ⅴ | 320 | 41.3 | 80 | 25.0 | ||||||
Living Situation | 0.395c | |||||||||
At home, alone | 206 | 25.4 | 38 | 18.4 | ||||||
At home, with spouse | 139 | 17.1 | 26 | 18.7 | ||||||
Home, living with someone else | 129 | 15.9 | 33 | 25.6 | ||||||
Communal living with assisted care / Special nursing home | 337 | 41.6 | 73 | 21.7 | ||||||
Number of drugs being taken at the first pharmacist home visit | 0.019c | |||||||||
0 – 9 | 530 | 69.6 | 100 | 18.9 | ref | |||||
10 - | 231 | 30.4 | 61 | 26.4 | 1.51 | (1.04, 2.19) | 0.030 | |||
Treatment adherence at first pharmacist home visit | 0.064c | |||||||||
Not adherent/only taking medication 1–2 times a week | 167 | 21.2 | 27 | 16.2 | 0.562d | 0.91 | (0.55, 1.51) | 0.717 | ||
Forgets to take medication 1–2 times a week | 230 | 29.2 | 59 | 25.7 | 1.55 | (1.03, 2.31) | 0.034 | |||
Takes medication as directed | 390 | 49.6 | 79 | 20.3 | ref | |||||
Appropriateness of anti-dementia drug therapy | 0.009e | |||||||||
Determined to be not appropriate | 42 | 5.3 | 16 | 38.1 | 2.85 | (1.46, 5.60) | 0.002 | |||
Determined to be appropriate | 753 | 94.7 | 147 | 19.5 | ref |
a: adjusted for sex and level of nursing care
b: Including subjects from whom responses were not obtained for each factor
c: Chi-square test
d: p for trend
e: Fisher's exact test