Table 1.
Parameters | Pre-treatment | Post-treatment (days) |
|||
---|---|---|---|---|---|
0 | 1 | 3 | 5 | 7 | |
Temperature (°C) | |||||
Group 1 | 39.10 ± 0.15ab,A | 38.69 ± 0.24AB | 38.38 ± 0.24B | 38.51 ± 0.23AB | 38.94 ± 0.26AB |
Group 2 | 39.10 ± 0.21ab,A | 38.75 ± 0.19AB | 38.69 ± 0.13AB | 38.56 ± 0.16B | 38.55 ± 0.15B |
Group 3 | 39.19 ± 0.14a,A | 39.01 ± 0.11A | 38.39 ± 0.19B | 38.38 ± 0.12B | 38.60 ± 0.10B |
Group 4 | 38.66 ± 0.11b | 38.38 ± 0.29 | 38.26 ± 0.17 | 38.37 ± 0.18 | 38.26 ± 0.42 |
Heart rate (min) | |||||
Group 1 | 130.00 ± 6.51 | 121.75 ± 4.20 | 129.25 ± 8.08 | 118.00 ± 5.61 | 116.25 ± 7.88 |
Group 2 | 120.00 ± 6.01 | 119.75 ± 10.27 | 117.38 ± 5.59 | 108.00 ± 7.56 | 102.00 ± 4.36 |
Group 3 | 129.88 ± 8.49 | 118.13 ± 7.10 | 120.00 ± 6.23 | 109.75 ± 8.81 | 110.50 ± 8.17 |
Group 4 | 130.75 ± 8.71 | 126.25 ± 7.75 | 123.14 ± 8.96 | 125.43 ± 11.30 | 117.14 ± 9.07 |
Respiration rate (min) | |||||
Group 1 | 44.25 ± 4.96A | 37.00 ± 1.81b,AB | 34.75 ± 2.42AB | 30.25 ± 4.13B | 31.25 ± 2.67B |
Group 2 | 34.00 ± 3.91 | 32.63 ± 3.57ab | 31.63 ± 3.80 | 31.50 ± 2.56 | 30.00 ± 2.27 |
Group 3 | 40.50 ± 2.97 | 37.50 ± 6.02ab | 39.50 ± 3.66 | 33.00 ± 1.46 | 32.38 ± 2.66 |
Group 4 | 37.75 ± 2.66 | 41.75 ± 1.83a | 34.57 ± 2.57 | 36.29 ± 2.71 | 36.57 ± 4.20 |
Different letters in the same rows (A, B) and columns (a, b) are statistically significant (P < 0.05). Group 1: 100 mg/kg COS, Group 2: 500 mg/kg COS, Group 3: 1000 mg/kg COS at intervals of 12 h, Group 4: No drug was given to the infected lambs.