Table 4.
Multiplex gastrointestinal panels, US Food and Drug Administration approved
Assay | Turnaround Time, h | Bacterial Targets | Viral Targets | Parasitic Targets | References |
---|---|---|---|---|---|
BDMax Enteric Bacterial Panela | 3 |
Campylobacter spp Salmonella spp Shigella/EIEC STEC |
— | — | Harrington et al,24 2015 |
BDMax Extended Enteric Bacterial Panelb | 3.5 | ETEC Plesiomonas shigelloides Vibrio spp Yersinia enterocolitica |
— | — | Simner et al,26 2017 |
BDMax Enteric Parasite Panel | 4.5 | — | — |
Cryptosporidium Entamoeba histolytica Giardia |
Madison-Antenucci et al,25 2016 |
bioMérieux FilmArray Gastrointestinal Panelc | 1 |
Campylobacter spp C difficile P shigelloides Salmonella spp Vibrio spp (cholerae) EAEC EPEC ETEC STEC (Escherichia coli O157) Shigella/EIEC |
Adenovirus 40/41 Astrovirus Norovirus Rotavirus Sapovirus |
Cryptosporidium Cyclospora cayetanensis E histolytica Giardia |
27, 29, 32, 34, 36 |
Hologic Prodesse ProGastro SSCS Assay | 4 |
Campylobacter spp Salmonella spp Shiga toxin 1 and 2 Shigella spp |
— | — | Buchan et al,28 2013 |
Luminex Verigene Enteric Pathogens Testd | 2 |
Campylobacter spp Salmonella spp Shigella spp Vibrio spp Y enterocolitica Shiga toxin 1 and 2 (stx1 and stx2) |
Norovirus Rotavirus |
— | Huang et al,29 2016 |
Luminex xTAG Gastrointestinal Pathogen Panele | 5 |
Campylobacter spp C difficile E coli O157 ETEC STEC Salmonella spp Shigella spp Vibrio cholera |
Adenovirus 40/41 Norovirus Rotavirus |
Cryptosporidium E histolytica Giardia |
29, 30, 31, 34 |
Abbreviations: EAEC, enteroaggregative E coli; EPEC, enteropathogenic E coli; ETEC, enterotoxigenic E coli; STEC, shiga-toxin–like producing E coli.
BDMax Enteric Bacterial Panel detects specific Campylobacter (coli and jejuni) species but only reports as a group.
BDMax Extended Enteric Bacterial Panel detects specific Vibrio (cholerae, parahaemolyticus, and vulnificus) species but only reports as a group.
FilmArray Gastrointestinal panel detects specific Campylobacter (coli, jejuni, and upsaliensis) and Vibrio (cholerae, parahaemolyticus, and vulnificus) species but only reports as a group. When STEC is detected, the assay then determines if it is an E coli O157 serotype.
Verigene Enteric Pathogen Test detects specific Campylobacter (coli, jejuni, and lari) and Vibrio (cholera and parahaemolyticus) species but only reports as a group.
xTAG Gastrointestinal Pathogen Panel detects specific Campylobacter (coli, jejuni, and lari) species but only reports as a group.