Extended Data Fig. 10. Sanger sequencing alignment of HH reference and base-edited clones reveal seamless editing.

Genomic DNA from expanded clones was sequenced and aligned to the reference (hg38) and visualized using SnapGene(v3.2.1). Red colored nucleotide indicates the location of the rs71542466 SNP in the reference. Highlighted red nucleotides indicate mismatches from the reference and yellow colored nucleotides indicate unresolved/heterozygous sequences.