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. 2020 Feb 2;295(14):4464–4476. doi: 10.1074/jbc.RA119.012015

Figure 2.

Figure 2.

Interactions between NHERF1 PDZ2 and CFTR. A, stereo view of the NHERF1 PDZ2-binding site (cyan) bound to the PDZ-binding motif of CFTR (beige). The 2Fo − Fc map is shown around the CFTR PDZ-binding motif contoured at 1.0 σ within 1.5 Å of the selected atoms. B, hydrophobicity surface structure of the NHERF1 PDZ2-binding site based on the Kyte-Doolittle scale with the most hydrophillic regions shown in blue and most hydrophobic regions shown in orange-red. The CFTR PDZ-binding motif is shown as a stick model in beige. Image was generated using Chimera (60).