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. Author manuscript; available in PMC: 2020 Oct 7.
Published in final edited form as: Trends Immunol. 2019 Oct 7;40(10):888–908. doi: 10.1016/j.it.2019.08.003

Figure 3.

Figure 3.

Immunogenic Dendritic Cells (DCs) in Infections. Immature DCs become immunogenic in response to microbial infections, tissue injury, or proinflammatory cytokines. This strong stimulation activates components of the innate immune system which then trigger Toll-like receptors on immature DCs. The result is their differentiation to a mature immunogenic state. Cytokines produced by these DCs facilitate the induction of T effector cell populations that clear the pathogen. Abbreviation: Th1/2/17, type 1/2/17 T helper cells.