Table 3.
Associations of exposure to traffic and pollutants with odds of ILA and ILA progression
| Odds of ILA versus no ILA |
Odds of ILA with progression versus no ILA on either CT |
Odds of ILA without progression versus no ILA on either CT |
|||
|---|---|---|---|---|---|
| Exposure | Model N | OR (95% CI) | Model N | OR (95% CI) | OR (95% CI) |
| Proximity to road (vs ≥400 m) | 1497 | 787 | |||
| <100m | 1.09 (0.68 to 1.73) | 1.30 (0.69 to 2.43) | – | ||
| 100–<200m | 1.21 (0.68 to 2.14) | 2.08 (0.98 to 4.44) | – | ||
| 200–<400m | 1.25 (0.76 to 2.06) | 1.00 (0.50 to 2.01) | – | ||
| PM2.5 | 1343 | 1.02 (0.85 to 1.23) | 709 | 1.14 (0.87 to 1.50) | 1.45 (0.92 to 2.28) |
| EC | 1344 | 1.27 (1.04 to 1.55) | 709 | 1.33 (1.00 to 1.77) | 1.32 (0.82 to 2.13) |
| O3 | 1495 | 0.91 (0.78 to 1.06) | 787 | 0.97 (0.78 to 1.21) | 0.92 (0.67 to 1.27) |
*
All models were adjusted for age, sex, body mass index, smoking status, packyears of smoking, any household smoking during adulthood, median value of owner-occupied housing in the census block group in 2000, education, primary occupation, cohort and date. OR’s for ILA without progression by proximity to road category are not shown due to small sample size and wide CIs. OR’s for associations with pollutants scaled per IQR in exposure: 1.3 μg/m3 in 2004–2008 PM2.5, 0.14 μg/m3 in 2004–2008 EC, and 1.8 ppb in 2004–2008 O3.
EC, elemental carbon; ILA, interstitial lung abnormalities; PM2 5, 5-year average offine particulate matter.