Figure 3. GA upregulates MHC Class II expression on B cells.

(A) Naive mice received a daily SC injection of 150 μg GA. On day 10 post-treatment onset, splenic B cells were isolated and analyzed (B and C) for expression of activation markers, (D–F) costimulatory molecules, and (G) the antigen-presenting molecule MHC Class II as well as (H) for secretion of cytokines. Data are shown as median; n = 4; *p < 0.05; Mann-Whitney U test. GA = glatiramer acetate.