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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: FASEB J. 2020 Feb 17;34(4):5363–5388. doi: 10.1096/fj.201901719RR

Figure 10. Proposed mechanism for TGFβ-dependent IGF-1 induction regulating the TGFβ-dependent profibrotic response.

Figure 10.

A schematic diagram of the molecular mechanisms required for TGFβ-dependent stimulation of IGF-1 and the TGFβ-initiated profibrotic cellular responses mediated by IGF-1R activation.