Table 5.
Animal colon segments (in vitro) | Human isolated colon (in vitro) | Adult colonic recording (in vivo) | Paediatric colonic recording (in vivo) |
---|---|---|---|
Neural peristalsis | Not yet studied | High-amplitude propagating contractions; long or short single motor pattern | High-amplitude propagating contraction; long or short single motor pattern |
Ripples | Not yet studied | Cyclic propagating motor pattern; intrahaustral activity | Cyclic propagating motor pattern |
Colonic motor complex | Repetitive motor pattern | Simultaneous pressure increases | Simultaneous pressure increases |
Colonic migrating motor complex | Not yet studied | Haustral boundary pressure transients | Not observed |
Neural retrograde propagating contraction | Not observed | Slow retrograde motor pattern | Not observed |
Isolated human colonic strips do not contain the entire neural circuits to generate complex motor patterns, but are useful to understand myogenic mechanisms, such as ripples associated with slow wave activity and slow phasic contractions and their modulation by neural inputs.