Table 1.
Characteristics of patients at first index prescription for antihypertensive, lipid-lowering or hypoglycemic treatment.
Variable | Branded anti-hypertensive (N = 427,641) | Generic anti-hypertensive (N = 558,508) | Branded lipid-lowering (N = 21,665) | Generic lipid-lowering (N = 25,694) | Branded hypo-glycemic (N = 101,045) | Generic hypo-glycemic (N = 99,993) |
---|---|---|---|---|---|---|
Age (years), mean (standard deviation) | 64.5 (15.4) | 63.3 (14.5) | 63.0 (12.8) | 62.4 (12.5) | 65.0 (13.9) | 62.7 (13.5) |
Sex: female | 54.3% | 54.5% | 50.3% | 54.3% | 49.5% | 50.2% |
Copayment waiver | 34.2% | 29.9% | 30.6% | 26.3% | 41.1% | 38.3% |
Hospitalization (ending in last 180 days) | 30.0% | 19.9% | 23.0% | 18.1% | 26.2% | 18.7% |
Hospitalization >14 days (ending in last 14 days) | 7.3% | 2.5% | 3.7% | 2.0% | 5.7% | 2.0% |
Hospitalization >14 days (ending in last 180 days) | 10.8% | 5.4% | 6.9% | 4.6% | 9.1% | 4.9% |
Index year: | ||||||
2007 | 0.7% | 0.6% | 0.1% | 0.4% | 1.0% | 0.7% |
2008 | 10.1% | 9.1% | 1.4% | 4.5% | 11.2% | 8.2% |
2009 | 22.4% | 22.0% | 33.3% | 16.9% | 22.4% | 18.4% |
2010 | 27.0% | 24.9% | 28.1% | 35.5% | 25.6% | 25.7% |
2011 | 20.6% | 23.3% | 22.1% | 25.4% | 22.2% | 25.4% |
2012 | 19.2% | 20.1% | 15.0% | 17.3% | 17.6% | 21.5% |
Specialty of prescriber: | ||||||
General practitioner | 67.7% | 78.5% | 68.9% | 75.4% | 77.5% | 81.7% |
Internal medicine specialist | 11.6% | 13.3% | 12.8% | 15.5% | 9.7% | 10.4% |
Hospital | 9.8% | 3.7% | 10.2% | 3.7% | 5.7% | 2.8% |
Other | 10.8% | 4.6% | 8.1% | 5.4% | 7.1% | 5.2% |
Recent myo-cardial infarction | 2.5% | 0.6% | 3.8% | 1.1% | 0.9% | 0.3% |
Recent cerebro-vascular event | 2.3% | 1.1% | 2.3% | 1.6% | 1.6% | 0.6% |
Any diagnosis in group of endocrine, nutritional or metabolic diseases or in group of diseases of circulatory system | 33.0% | 16.6% | 25.3% | 15.5% | 28.0% | 15.5% |
Previous use of antihypertensive, lipid-lowering or hypoglycemic medicines | 67.5% | 64.1% | 73.0% | 69.0% | 81.3% | 76.4% |
Previous use of injectable insulins | 1.9% | 1.4% | 2.0% | 1.4% | 3.2% | 2.5% |
Previous use of oral hypoglycemic drugs | 12.7% | 11.5% | 14.6% | 13.0% | 39.2% | 21.6% |