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. 2020 Apr 6;10:5964. doi: 10.1038/s41598-020-62318-y

Table 1.

Characteristics of patients at first index prescription for antihypertensive, lipid-lowering or hypoglycemic treatment.

Variable Branded anti-hypertensive (N = 427,641) Generic anti-hypertensive (N = 558,508) Branded lipid-lowering (N = 21,665) Generic lipid-lowering (N = 25,694) Branded hypo-glycemic (N = 101,045) Generic hypo-glycemic (N = 99,993)
Age (years), mean (standard deviation) 64.5 (15.4) 63.3 (14.5) 63.0 (12.8) 62.4 (12.5) 65.0 (13.9) 62.7 (13.5)
Sex: female 54.3% 54.5% 50.3% 54.3% 49.5% 50.2%
Copayment waiver 34.2% 29.9% 30.6% 26.3% 41.1% 38.3%
Hospitalization (ending in last 180 days) 30.0% 19.9% 23.0% 18.1% 26.2% 18.7%
Hospitalization >14 days (ending in last 14 days) 7.3% 2.5% 3.7% 2.0% 5.7% 2.0%
Hospitalization >14 days (ending in last 180 days) 10.8% 5.4% 6.9% 4.6% 9.1% 4.9%
Index year:
2007 0.7% 0.6% 0.1% 0.4% 1.0% 0.7%
2008 10.1% 9.1% 1.4% 4.5% 11.2% 8.2%
2009 22.4% 22.0% 33.3% 16.9% 22.4% 18.4%
2010 27.0% 24.9% 28.1% 35.5% 25.6% 25.7%
2011 20.6% 23.3% 22.1% 25.4% 22.2% 25.4%
2012 19.2% 20.1% 15.0% 17.3% 17.6% 21.5%
Specialty of prescriber:
General practitioner 67.7% 78.5% 68.9% 75.4% 77.5% 81.7%
Internal medicine specialist 11.6% 13.3% 12.8% 15.5% 9.7% 10.4%
Hospital 9.8% 3.7% 10.2% 3.7% 5.7% 2.8%
Other 10.8% 4.6% 8.1% 5.4% 7.1% 5.2%
Recent myo-cardial infarction 2.5% 0.6% 3.8% 1.1% 0.9% 0.3%
Recent cerebro-vascular event 2.3% 1.1% 2.3% 1.6% 1.6% 0.6%
Any diagnosis in group of endocrine, nutritional or metabolic diseases or in group of diseases of circulatory system 33.0% 16.6% 25.3% 15.5% 28.0% 15.5%
Previous use of antihypertensive, lipid-lowering or hypoglycemic medicines 67.5% 64.1% 73.0% 69.0% 81.3% 76.4%
Previous use of injectable insulins 1.9% 1.4% 2.0% 1.4% 3.2% 2.5%
Previous use of oral hypoglycemic drugs 12.7% 11.5% 14.6% 13.0% 39.2% 21.6%