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. 2020 Apr 6;10:5969. doi: 10.1038/s41598-020-62846-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Venn diagrams illustrating differential gene expression in HMEECs treated with urban particle, S. pneumoniae or co-treatment with respect to the control (untreated). The global gene expression analysis was performed using total RNA microarray analysis of HMEECs. (a) Differentially expressed gene in all three treatments with respect to untreated cells. (b) Venn diagram showing differentially expressed genes in HMEECs treated with UP, S. pneumoniae or co-treatment.