Table 3.
Associations between plasma LRG1 tertile with peripheral arterial occlusive disease (PAOD) and cardiovascular disease (CVD).
| Independent variables in model (dependent variable: PAOD) | Model 1 | Model 2 | ||
|---|---|---|---|---|
| Odds Ratio (95% CI) | p value | Odds Ratio (95% CI) | p value | |
| Age | 1.10 (1.02–1.18) | 0.012* | 1.14 (1.03–1.25) | 0.01* |
| Gender (Male) | 1.79 (0.43–7.42) | 0.425 | 1.96 (0.46–8.32) | 0.362 |
| Diabetes | 4.29 (0.89–20.80) | 0.07 | 4.36 (0.80–23.70) | 0.088 |
| Albumin (g/dL) | 1.34 (0.20–9.08) | 0.766 | ||
| Hemoglobin (g/dL) | 2.28 (1.07–4.83) | 0.033* | ||
| Ca×P product (mg2/dL2) | 1.28 (0.88–1.86) | 0.2 | ||
| hsCRP (mg/dL) | 0.99 (0.93–1.05) | 0.708 | ||
| Plasma LRG1 tertile | 2.97 (1.07–8.25) | 0.036* | 3.49 (1.13–10.76) | 0.03* |
| Independent variables in model (dependent variable: CVD) | Odds Ratio (95% CI) | p value | OR (95% CI) | p value |
| Age | 1.04 (1.01–1.07) | 0.016* | 1.05 (1.01–1.09) | 0.011* |
| Gender (Male) | 0.72 (0.33–1.55) | 0.395 | 0.70 (0.32–1.53) | 0.371 |
| Diabetes | 2.38 (1.13–5.02) | 0.023* | 2.41 (1.12–5.15) | 0.024* |
| Albumin (g/dL) | 1.57 (0.54–4.58) | 0.412 | ||
| Hemoglobin (g/dL) | 1.01 (0.73–1.41) | 0.951 | ||
| Ca×P product (mg2/dL2) | 1.02 (0.78–1.33) | 0.883 | ||
| hsCRP (mg/dL) | 1.01 (0.98–1.03) | 0.736 | ||
| Plasma LRG1 tertile | 1.57 (1.00–2.47) | 0.049* | 1.65 (1.02–2.68) | 0.043* |
Multivariate logistic regression analysis with two models: model 1 (age, gender, diabetes mellitus) and model 2 (age, gender, diabetes mellitus, albumin, hemoglobin, calcium phosphate product and hsCRP), were used to investigate the association between LRG-1 tertiles and baseline co-morbidities.