Table 4.

Associations between plasma LRG1 concentration with peripheral arterial occlusive disease (PAOD) and cardiovascular disease (CVD).

Independent variables (dependent variable: PAOD)	Model 1		Model 2
	Odds Ratio (95% CI)	p value	Odds Ratio (95% CI)	p value
Age	1.11 (1.03–1.20)	0.009*	1.14 (1.04–1.26)	0.009*
Gender (Male)	1.76 (0.42–7.39)	0.439	1.97 (0.46–8.50)	0.365
Diabetes	7.14 (1.28–39.89)	0.025*	7.67 (1.16–50.51)	0.034*
Albumin (g/dL)			1.17 (0.16–8.73)	0.878
Hemoglobin (g/dL)			2.15 (1.03–4.51)	0.042*
Ca×P product (mg2/dL2)			0.99 (0.94–1.06)	0.842
hsCRP (mg/dL)			1.31 (0.90–1.92)	0.164
Plasma LRG1 (μg/ml)	1.06 (1.02–1.12)	0.011*	1.07 (1.02–1.12)	0.012*
Independent variables (dependent variable: CVD)	Odds Ratio (95% CI)	p value	OR (95% CI)	p value
Age	1.04 (1.01–1.07)	0.017*	1.05 (1.01–1.09)	0.011*
Gender (Male)	0.70 (0.32–1.52)	0.365	0.68 (0.31–1.50)	0.341
Diabetes	2.59 (1.23–5.46)	0.013*	2.67 (1.24–5.73)	0.012*
Albumin (g/dL)			1.52 (0.52–4.49)	0.446
Hemoglobin (g/dL)			1.01 (0.72–1.41)	0.963
Ca×P product (mg2/dL2)			1.01 (0.98–1.03)	0.661
hsCRP (mg/dL)			1.02 (0.78–1.33)	0.884
Plasma LRG1 (μg/ml)	1.03 (1.00–1.05)	0.028*	1.03 (1.00–1.06)	0.025*

Multivariate logistic regression analysis with two models: model 1 (age, gender, diabetes mellitus) and model 2 (age, gender, diabetes mellitus, albumin, hemoglobin, calcium phosphate product and hsCRP), were used to investigate the association between LRG1 concentration and baseline co-morbidities.