Table 5.

Different Titration Methods and Conversion of Gabapentin and Pregabalin for Patients with Intractable Pain Requiring a Rapid Dose Increase

Day	Gabapentin								Pregabalin
	TID			Total daily dose	QID					BID		Total daily dose	TID
	7A	1P	7P		7A	1P	7P	11P	7A	7P	7A		3P	11P
1	-	-	300	300	-	-	-	300	50	50	100	25	25	50
2	300	-	300	600	100	100	100	300	75	75	150	50	50	50
3	300	300	300	900	200	200	200	300	100	100	200	50	50	100
4-6	400	400	400	1,200	300	300	300	300	150	150	300	75	75	150
7-10	500	500	500	1,500	300	300	300	600	200	200	400	100	100	200
11-14	600	600	600	1,800	400	400	400	600	250	250	500	125	125	250
15	800	800	800	2,400	600	600	600	600	300	300	600	150	150	300

TID: ter in die; three times a day, QID: quarter in die; four times in a day, BID: bis in die; twice in a day, -: not available.

Modified from the article of Yang et al. (Korean J Anesthesiol 2013; 65: 48-54) [52].