Table 1.
Clinical characteristics
| Clinical parameter | |
|---|---|
| Median age at diagnosis, yr (range) | 51.7 (32.6–71.2) |
| Sex, n (%) | |
| Male | 19 (83) |
| Female | 4 (17) |
| Type of lesion, n (%) | |
| Light chain deposition disease | 22 (96) |
| Heavy chain deposition disease | 1 (4) |
| Light chain clonality, n (%) | |
| Kappa | 17 (74) |
| Lambda | 5 (22) |
| Renal presentation | |
| Median creatinine (mg/dl), (range) | 3 (0.8–12) |
| Median proteinuria (g/24 h), (range) | 3 (0–22) |
| Chronic kidney disease stage, n (%) | |
| I–II | 2 (9) |
| III | 4 (17) |
| IV | 12 (52) |
| V and/or end-stage renal disease | 5 (22) |
| Comorbidities, n | |
| Other hematologic diagnoses, n | |
| Monoclonal gammopathy of unknown significance | 2 |
| Chronic lymphocytic lymphoma | 1 |
| Multiple myeloma | 1 |
| Solid malignancies, n (%) | 4 (13) |
| Diabetes, n (%) | 4 (13) |
| Hypertension, n (%) | 11 (57) |
| Cardiac involvement, n (%) | 4 (17) |