Figure 11.

Combination of capture-shrinkage and cortical sliding. (a) Dependence of the average distance between the center of the cell and the MTOC ${\overline{d}}_{\text{MC}}$ on the average MTOC-IS distance ${\overline{d}}_{\text{MIS}}$ is shown. (b and c) A probability density plot for the spatial distribution of attached dynein is given. (b) t = 50 s, ${\overline{d}}_{\text{MIS}}$ ∼ 4.5 μm. (c) t = 60 s, ${\overline{d}}_{\text{MIS}}$ ∼ 1.5 μm. (d) Repositioning times as a function of the density of capture-shrinkage dynein ρ_IS for four different values of the cortical sliding area density ${\tilde{\rho }}_{\text{IS}}$ are shown. The error bars are represented by dashed lines and are plotted only if bigger than a symbol size. (e–g) Snapshots from simulation are given. The blue, red, and bold yellow curves correspond to MTs without dynein and with capture-shrinkage and cortical sliding, respectively. Black dots depict positions of attached dynein motors. (e) d_MIS = 4.5 μm, (f) d_MIS = 2.5 μm, and (g) d_MIS = 1 μm. To see this figure in color, go online.