Fig. 1.
Study design. Asterisk indicates telephone calls by investigators to monitor insulin titration weekly between site visits for all participants, unless investigators are attending the study site for sensor replacement. Participant has option to come to site on day −10 and day 74 for sensor replacement. CGM Continuous glucose monitoring, Gla-300 insulin glargine 300 U/mL, HbA1c glycated haemoglobin, IDeg-100 insulin degludec 100 U/mL, MDI multiple daily injection, QD once daily, R randomisation, SMPG self-monitored plasma glucose, T1D type 1 diabetes