Why carry out this study?

Nocturnal hypoglycemia frequently occurs in people with type 1 diabetes (T1D) and causes great harm.

Capillary blood glucose testing remains the fundamental way of self-monitoring in the clinic.

How can we make full use of self-monitoring profiles to evaluate and prevent nocturnal hypoglycemia in T1D?

What was learned from the study?

Nocturnal hypoglycemia constituted nearly one-third of hypoglycemic events in people with T1D based on continuous glucose monitoring.

Fasting blood glucose below 6.2 mmol/L or blood glucose at bedtime below 6.8mmol/L indicates a high risk of hypoglycemia during the nighttime.

The BGn model derived from variation of capillary glucose during the daytime presented a high specificity to discriminate patients with increased risk of nocturnal hypoglycemia.