Table 4.
Effects of different clinical characteristics on the hazard ratio of endpoint events
| Variables | CVD events | Cardiovascular events | Cerebrovascular events | Cardiac and cerebral vascular death |
|---|---|---|---|---|
| Gender | 0.73 (0.59–0.90) | 0.70 (0.53–0.92) | 0.77 (0.56–1.08) | 0.44 (0.29–0.67) |
| Age (years) | 1.03 (1.02–1.05) | 1.04 (1.02–1.05) | 1.03 (1.01–1.05) | 1.10 (1.07–1.13) |
| Duration of diabetes (years) | 1.02 (1.00–1.03) | 1.02 (1.00–1.04) | 1.02 (0.99–1.04) | 1.04 (1.01–1.06) |
| Drug therapy | 1.37 (0.91–2.06) | 1.86 (1.01–3.42) | 0.98 (0.57–1.71) | 1.49 (0.65–3.41) |
| BMI (kg/m2) | 1.04 (1.01–1.07) | 1.06 (1.02–1.10) | 1.01 (0.96–1.06) | 1.04 (0.98–1.10) |
| Waist circumference (cm) | 1.03 (1.02–1.04) | 1.03 (1.02–1.05) | 1.02 (1.00–1.04) | 1.04 (1.02–1.06) |
| Neck circumference (cm) | 1.03 (1.00–1.06) | 1.04 (1.00–1.08) | 1.02 (0.98–1.07) | 1.03 (0.98–1.09) |
| SBP (mmHg) | 1.01 (1.01–1.02) | 1.01 (1.00–1.02) | 1.02 (1.01–1.03) | 1.02 (1.01–1.04) |
| DBP (mmHg) | 0.99 (0.98–1.01) | 1.00 (0.98–1.01) | 0.99 (0.98–1.01) | 0.99 (0.96–1.01) |
| FPG (mmol/L) | 1.01 (0.97–1.05) | 0.95 (0.90–1.01) | 1.07 (1.02–1.13) | 1.00 (0.93–1.09) |
| Hpg (mmol/L) | 1.01 (0.99–1.02) | 1.00 (0.98–1.03) | 1.01 (1.00–1.03) | 1.01 (0.99–1.04) |
| HbA1c (%) | 1.08 (1.01–1.14) | 1.03 (0.94–1.12) | 1.14 (1.05–1.24) | 1.16 (1.05–1.29) |
| TG (mmol/L) | 1.04 (0.97–1.11) | 1.01 (0.91–1.11) | 1.07 (0.97–1.18) | 0.99 (0.85–1.15) |
| TC (mmol/L) | 1.08 (1.00–1.16) | 1.03 (0.92–1.14) | 1.14 (1.04–1.25) | 0.95 (0.79–1.13) |
| HDL-cholesterol (mmol/L) | 0.88 (0.67–1.15) | 0.60 (0.40–0.89) | 1.26 (0.92–1.74) | 0.47 (0.25–0.89) |
| LDL-cholesterol (mmol/L) | 1.08 (0.95–1.22) | 1.16 (0.99–1.36) | 0.97 (0.80–1.18) | 0.97 (0.77–1.23) |
| Alanine aminotransferase (10 U/L) | 0.99 (0.92–1.08) | 1.02 (0.92–1.13) | 0.95 (0.83–1.09) | 0.83 (0.68–1.03) |
| Blood urea nitrogen (10 mmol/L) | 0.98 (0.89–1.08) | 0.92 (0.69–1.22) | 1.01 (0.92–1.11) | 1.02 (0.91–1.14) |
| Creatinine (10 mmol/L) | 1.03 (0.99–1.06) | 1.01 (0.96–1.06) | 1.05 (1.00–1.11) | 1.05 (0.99–1.12) |
| Urine acid (10 mmol/l) | 1.02 (1.01–1.03) | 1.02 (1.00–1.03) | 1.02 (1.00–1.03) | 1.02 (1.00–1.04) |
| I-FRS | 1.09 (1.06–1.13) | 1.07 (1.04–1.11) | 1.12 (1.08–1.18) | 1.16 (1.09–1.22) |
Values in table are presented as the hazard ratio with the 95% confidence interval given in parenthesis