Table 2.
Comparative analysis of genes modulated in satiated macrophages and IPF patients.
| Description | Symbol | Fold reduction (–log2) |
|---|---|---|
| Laminin B1 | Lamb1 | 5.73342 |
| Collagen, type I, alpha 2 | Col1a2 | 3.72915 |
| Collagen, type Ill, alpha | Col3a1 | 3.65418 |
| Secreted acidic cysteine rich glycoprotein | Sparc | 3.26993 |
| Lysyl oxidase-like 1 | Loxl1 | 3.17508 |
| Collagen, type V, alpha 2 | Col5a2 | 3.16363 |
| Cysteine rich protein 61 | Cyr61 | 2.999 |
| Bone morphogenetic protein 1 | Bmp1 | 2.37722 |
| Serine (or cysteine) peptidase, inhibitor, clade G, member 1 | Serping1 | 2.85737 |
| Collagen, type VI, alpha 2 | Col6a2 | 2.60818 |
| Laminin, beta 2 | Lamb2 | 2.51054 |
| Syntaxin 1A (brain) | Stx1a | 2.36814 |
| Follistatin-like 1 | Fstl1 | 2.35297 |
| Vasorin | Vasn | 2.27123 |
| Collagen, type VI, alpha 1 | Col6a1 | 2.23102 |
| Cysteine rich transmembrane BMP regulator 1 (chordin like) | Crim1 | 2.22188 |
| Lysyl oxidase-like 3 | Loxl3 | 1.92259 |
| Niemann Pick type C1 | Npc1 | 1.75604 |
| Collagen, type I, alpha 1 | Col1a1 | 1.63809 |
| Scavenger receptor cysteine rich domain containing (5 domains) | Ssc5d | 1.53205 |
| platelet-derived growth factor C polypeptide | Pdgfc | 1.48094 |
| Tissue inhibitor of metalloproteinase 2 | Timp2 | 1.38781 |
| Phospholipid transfer protein | Pltp | 1.29273 |
| Latent transforming growth factor beta binding protein 3 | Ltpb3 | 1.24257 |
| C-type lectin domain family 11, member a | Clec11a | 1.17277 |
| Filamin, alpha | Flna | 1.16859 |
| Elastin microfibril interfacer 2 | Emilin2 | 1.13144 |
| Laminin, gamma 1 | Lamc1 | 1.10757 |
A list of all the genes that were significantly down-regulated in satiated macrophages and significantly changed in samples for IPF patients. Genes labeled in yellow were up-regulated while genes labeled in gray were down-regulated in IPF patients.