Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 31;10:363. doi: 10.3389/fonc.2020.00363

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Lan, Yao, Sun, Li, Liu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Identification of the involvement of the SNHG6/HNRNPA1/PKM axis in the metabolic mechanism of colorectal cancer (CRC). (A,B) Kyoto Encyclopedia of Genes and Genomes (KEGG) and Wikipathway cancer pathway enrichment analysis of mRNA interacting directly with SNHG6, as given by ENCORI. (C) A total of 181 differentially expressed genes related to SNHG6 were identified in GSE103479. (D) KEGG pathway enrichment analysis of the differentially expressed genes related to SNHG6 as found in GSE103479. (E) Through the intersection of genes from metabolic pathways enrichment analyses in the (A,B,D), it was found that pyruvate kinase M (PKM) was the only overlapping gene. (F) The ratio of PKM2/PKM1 was downregulated in shSNHG6 RKO cells. Ns, P > 0.05; ^*P < 0.05; ^**P < 0.01; ^***P < 0.001; ^****P < 0.0001.