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. 2020 Mar 31;8:202. doi: 10.3389/fcell.2020.00202

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Copyright © 2020 Tesovnik, Kovač, Pohar, Hudoklin, Dovč, Bratina, Trebušak Podkrajšek, Debeljak, Veranič, Bosi, Piemonti, Ihan and Battelino.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chloroquine miRNA/DOTAP inhibition. Chloroquine (CQ) inhibition of hsa-miR-122-5p, hsa-miR-455-5p, hsa-miR-375-3p, hsa-miR-129-5p DOTAP vesicle stimulation effect on expression of early transition activation marker (CD69) on panels (A) CD4+ and (B) CD8+ T-cells and degranulation marker (CD107a) on panels (C) CD8+ T-cells and (D) CD56+ NK cells after 21h stimulation [box plot: Q1, median, Q3; whisker lines: 1.5 IQR; N = 6; K- negative control, P-values under blue lines represent a paired Hedges’ g mean difference analysis significance: P < 0.05 significant difference].