Table 1.

Autoantibodies recorded in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome patients.

Target structure	Autoantigen
Neurotransmitter	5-hydroxytryptamine (4, 5)
Neurotransmitter receptors	Muscarinic M1 acetylcholine receptor (6) Muscarinic M3/4 acetylcholine receptor ß2 adrenergic receptor (7) μ-opioid receptor, 5-hydroxytryptamine receptor, dopamine receptor D2 (6)
Cell nucleus	Nuclear envelope (8, 9) Single-stranded DNA (10) Double-stranded DNA (4)
Cytoplasmic membrane	Intermediate filaments (8) Phosphatidylserine (4) Phospholipids, gangliosides (5)
Mitochondria	Heat shock protein 60 (11) Cardiolipin (4, 12, 13)
Neo-antigens	Oleic acid (14) Palmitic acid, myristic acid, S-farnesyl-L-cysteine, malondialdehyde, azelaic acid (15) NO-tyrosine (14, 15) NO-phenylalanine (14, 15) NO-arginine, NO-tryptophan, NO-cysteinyl (14) NO-Bovine serum albumin (16) NO-histidine, NO-creatine, NO-asparagine (15)
Other targets	dUTPase (17) Endothelial cells, neuronal cells (4)

NO-, nitrosylated; dUTPase, deoxyuridine 5′-triphosphate nucleotide hydrolase.