Figure 3.

BTLA⁺DCs in active TB showed a decreased expression of the DC maturation marker CD83. The expression of the maturation surface marker CD83 on DCs was determined by flow cytometry (n = 12). The gating strategy is shown in Figure S1. (A,B) show the positive rate (%) of CD83 expression between BTLA⁺ DCs and BTLA⁻ DCs of HCs. (C,D) show the MFI of CD83 expression between BTLA⁺ DCs and BTLA⁻ DCs in HCs. (E,F) show the positive rate (%) of CD83 expression between BTLA⁺ DCs and BTLA⁻ DCs in APT patients. (G,H) show the MFI of CD83 expression between BTLA⁺ DCs and BTLA⁻ DCs in APT patients. (I,J) show the positive rate (%) (I) and MFI (J) of CD83 expression in BTLA⁺ tDCs/mDCs/pDCs between HCs and APT patients. (K,L) show the positive rate (%) (I) and MFI (K) of CD83 expression in BTLA⁻ tDCs and mDCs between HCs and APT patients. The P-value is shown in each column (Student t-test). ^*P < 0.05, ^**P < 0.01, ^***P < 0.001.