Table 2.
Association between surgical outcomes and colon-cancer locations
| Outcome | No. of patients (%) |
ORa (95% CI) | P-value | |
|---|---|---|---|---|
| LCC (n = 18,936) | RCC (n = 16,927) | |||
| No complication | 16,315 (86.2) | 14,238 (84.1) | 1 [Reference] | |
| Any complicationb | 2,621 (13.8) | 2,689 (15.9) | 1.01 (0.95–1.07) | 0.750 |
| Minor complicationsc | 1,434 (7.6) | 1,369 (8.1) | 0.98 (0.90–1.06) | 0.642 |
| Major complicationsd | 1,419 (7.5) | 1,503 (8.9) | 1.00 (0.92–1.08) | 1.000 |
| Superficial SSI | 994 (5.3) | 848 (5.0) | 0.95 (0.86–1.05) | 0.312 |
| Deep SSI | 132 (0.7) | 119 (0.7) | 0.96 (0.74–1.24) | 0.759 |
| Organ-specific SSI | 498 (2.6) | 479 (2.8) | 1.08 (0.94–1.23) | 0.277 |
| Wound disruption | 165 (0.9) | 116 (0.7) | 0.69 (0.54–0.89) | 0.003 |
| Pneumonia | 273 (1.4) | 390 (2.3) | 1.23 (1.04–1.45) | 0.016 |
| Re-intubation | 246 (1.3) | 321 (1.9) | 1.04 (1.04–1.04) | <0.001 |
| Pulmonary embolism | 97 (0.5) | 135 (0.8) | 1.25 (0.95–1.65) | 0.111 |
| Ventilator dependence | 213 (1.1) | 216 (1.3) | 0.89 (0.89–0.89) | <0.001 |
| Renal progressive insufficiency | 102 (0.5) | 100 (0.6) | 0.91 (0.68–1.22) | 0.526 |
| ARF | 66 (0.4) | 66 (0.4) | 0.94 (0.94–0.95) | <0.001 |
| CVA | 45 (0.2) | 70 (0.4) | 1.14 (0.77–1.69) | 0.513 |
| Coma | 5 (0) | 0 (0) | NA | |
| Cardiac arrest | 76 (0.4) | 94 (0.6) | 1.04 (0.76–1.43) | 0.806 |
| MI | 115 (0.6) | 141 (0.8) | 0.94 (0.73–1.22) | 0.631 |
| Sepsis | 405 (2.1) | 406 (2.4) | 1.06 (0.91–1.23) | 0.454 |
| Septic shock | 212 (1.1) | 222 (1.3) | 0.95 (0.78–1.16) | 0.610 |
| UTI | 359 (1.9) | 393 (2.3) | 0.91 (0.78–1.06) | 0.230 |
| DVT | 150 (0.8) | 209 (1.2) | 1.28 (1.02–1.60) | 0.033 |
| Re-operation | 56 (0.3) | 41 (0.2) | 0.77 (0.50–1.18) | 0.235 |
| 30-day mortality | 175 (0.9) | 251 (1.5) | 1.04 (0.85–1.27) | 0.703 |
| Operation time of colectomye, min | ||||
| <160 | 8,955 (47.3) | 12,107 (71.5) | 1 [Reference] | |
| ≥160 | 9,981 (52.7) | 4,820 (28.5) | 0.38 (0.36–0.39) | <0.001 |
| Length of hospital staye, days | ||||
| <5 | 8,740 (46.2) | 6,945 (41.0) | 1 [Reference] | |
| ≥5 | 10,196 (53.8) | 9,982 (59.0) | 1.10 (1.05–1.15) | <0.001 |
LCC, left colon cancer; RCC, right colon cancer; OR, odds ratio; CI, confidential interval; SSI, surgical-site infection; ARF, acute renal failure, CVA, cerebrovascular accident; MI, myocardial infraction; UTI, urinary-tract infection; DVT, deep vein thrombosis; NA, not applicable.
Adjusted for age, sex, race, smoking, functional status, American Society of Anesthesiologists classification, body mass index, weight loss >10%, diabetes, congestive heart failure, previous cardiac surgery, previous percutaneous coronary intervention, myocardial infraction, transient ischemic attack, hypertension, pneumonia, chronic obstructive pulmonary disease, cerebrovascular accident, and hemiplegia.
Including one or more of the complications listed in Table 2.
Including superficial SSI, UTI, DVT, and/or thrombophlebitis.
Including deep SSI, organ-space SSI, wound disruption, pneumonia, re-intubation, pulmonary embolism, greater than 48-hour post-operative ventilator-assisted respiration, progressive renal insufficiency, ARF, CVA, cardiac arrest requiring cardiopulmonary resuscitation, MI, sepsis, and septic shock.
Median value was based on the distribution of patients with LCC colectomy.