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. 2020 Apr 7;2020(4):rjaa070. doi: 10.1093/jscr/rjaa070

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Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Histological examination. (I) Microscopic examination of the biopsy: A. Glandular and focal papillar pattern , HE stain x200 B. Hobnail morphology of tumoral cells, HE stain x400 C. Nests of neoplastic clear cells, HE stain x400 D. Nuclear immunoreactivity with anti-PAX8 antibody, x200 E. Nuclear immunoreactivity with anti-HNF-1β antibody, x200 F. Wild type pattern with anti-p53 antibody, x200. (II) Surgical specimen. Resection of the parietal mass with free margins after radiotherapy. (III) Microscopic examination of resected specimen: A. Nodular lesion involving dermis and hypodermis, HE x5 B. Hemorrhage, fibrotic and necrotic changes, HE x50 C. Microcystic predominant pattern, HE x100.

Histological examination. (I) Microscopic examination of the biopsy: A. Glandular and focal papillar pattern , HE stain x200 B. Hobnail morphology of tumoral cells, HE stain x400 C. Nests of neoplastic clear cells, HE stain x400 D. Nuclear immunoreactivity with anti-PAX8 antibody, x200 E. Nuclear immunoreactivity with anti-HNF-1β antibody, x200 F. Wild type pattern with anti-p53 antibody, x200. (II) Surgical specimen. Resection of the parietal mass with free margins after radiotherapy. (III) Microscopic examination of resected specimen: A. Nodular lesion involving dermis and hypodermis, HE x5 B. Hemorrhage, fibrotic and necrotic changes, HE x50 C. Microcystic predominant pattern, HE x100.