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. 2020 Mar 31;11:299. doi: 10.3389/fgene.2020.00299

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Copyright © 2020 Zhu, Liu, Xu, Liu, Xie, Sham, Sha and Cheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Maternal Dgcr8 regulates mitosis during early embryonic development in Mdgcr8 and MZdgcr8. (A) Representative images of 25 hpf WT, Mdgcr8 and MZdgcr8 embryos showing the distribution of PH3 immunolabeling cells (B) and quantification of positive cells in the hindbrain before the otic vesicle in the dashed box region (N = 3). (C) Mitotic centrosomes were detected using γ-tubulin immunostaining. ***p < 0.001 and ****p < 0.0001.