Figure 2.

Hazard ratios and 95% CIs for combination of LDL cholesterol and diabetic status in relation to incident cancer. A. Multivariable-adjusted hazard ratios of incident cancer in participants without diabetes. B. Multivariable-adjusted hazard ratios of incident cancer in participants with diabetes. The solid lines are multivariate-adjusted hazard ratios and the dashed lines indicate 95% confidence intervals derived from restricted cubic spline regression. Four knots were located at the 25%, 50%, and 75% percentiles for serum LDL cholesterol. The Cox regression was adjusted for age, sex, BMI, family history of cancer, smoking, drinking, education status, physical activity, consumption of vegetables and fruit, insulin therapy, lipid-lowering medication, and systolic blood pressure at baseline.