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. 2020 Mar 1;10(3):884–896.

Figure 2.

Figure 2

MKP1 inhibits HCC migration and invasion in vitro and in vivo. A and B. Western blot analysis of the expression of MKP1 in HCC cell lines. C and D. Western blot analysis to detect the expression of MKP1 in MHCC97H and HCCLM3 cells stably transfected with a control or a His-MKP1-overexpressing plasmid. E-H. Transwell migration assays in MHCC97H and HCCLM3 cells transfected with a control or a His-MKP1-overexpressing plasmid. *P < 0.01. I and J. Western blot analysis to detect the expression of MMP2 and MMP9 in MHCC97H and HCCLM3 cells transfected with a control or a His-MKP1-overexpressing plasmid. K and L. Incidence of lung metastasis in the MHCC97h-control and MHCC97h-His-MKP1 groups. *P < 0.01.