Figure 2.

Phylogenetic tree summarizing established links between female reproductive tract microbiome and gynecological cancers. We constructed a phylogenetic tree using evolutionary distance with phyloT software [95] to describe the phylogenetic similarity of all microbiome reported to be associated with gynecological cancer in human studies. From the inside out, representing from the wider (kingdom) to the more specific (species) taxonomy. Based on the phenotype of the various studies included, the bacterial taxonomy is labeled according to the source of publication (colored dots) and shaded (OC = ovarian cancer, light red; CC = cervical cancer, light yellow; EC = endometrial cancer, light blue) based on the cancer types.