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. 2020 Mar 18;12(4):e09271. doi: 10.15252/emmm.201809271

Figure EV4. Analysis of liver vasculature and function in Rbpj iΔ EC mice.

Figure EV4

  • A
    Representative confocal images showing collagen IV+ blood vessels (red) in liver sections from Rbpj iΔEC mice and littermate controls 6 weeks after tamoxifen injection. Scale bar 50 μm.
  • B
    Quantification of microvessel density and average vessel size in control (n = 3) and Rbpj iΔEC (n = 3) mice. Data represent mean ± SEM, Welch's t‐test.
  • C–E
    Representative images of hematoxylin and eosin (H&E) (C), Sirius red (D), and Prussian blue (E) staining of liver sections from control and NICDiOE‐EC mice. n = 4, scale bar 100 μm.
  • F, G
    Plasma levels of albumin (F) and urea (G) in control and Rbpj iΔEC mice. n = 4, data represent mean ± SEM, unpaired t‐test.
  • H–J
    Plasma levels of alanine aminotransferase (ALAT) (H), aspartate aminotransferase (ASAT) (I), and alkaline phosphatase (ALP) (J) in control and Rbpj iΔEC mice. n = 4, data represent mean ± SEM, unpaired t‐test.