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. 2020 Mar 18;12(4):e09271. doi: 10.15252/emmm.201809271

Figure 6. Endothelial‐specific Notch modulation alters glucose uptake in muscle.

Figure 6

  • A
    Schematic illustration of 2‐DG uptake assay protocol for control and NICDiOE‐EC mice.
  • B
    Blood glucose levels of control and NICDiOE‐EC mice during the 2‐DG uptake assay. n = 5, data represent mean ± SEM, unpaired t‐test.
  • C
    Plasma insulin levels of control and NICDiOE‐EC mice during the 2‐DG uptake assay. n = 5, data represent mean ± SEM, unpaired t‐test.
  • D
    2‐DG uptake levels in skeletal muscle of control and NICDiOE‐EC mice. n = 5, data represent mean ± SEM, unpaired t‐test.
  • E
    2‐DG uptake levels in visceral white adipose tissue (vWAT) of control (n = 4) and NICDiOE‐EC (n = 5) mice. Data represent mean ± SEM, unpaired t‐test.
  • F
    Schematic illustration of 2‐DG uptake assay protocol for control and Rbpj iΔEC mice.
  • G
    Blood glucose levels of control and Rbpj iΔEC mice during the 2‐DG uptake assay. n = 5, data represent mean ± SEM, unpaired t‐test.
  • H
    Plasma insulin levels of control and Rbpj iΔEC mice during the 2‐DG uptake assay. n = 5, data represent mean ± SEM, unpaired t‐test.
  • I
    2‐DG uptake levels in skeletal muscle of control and Rbpj iΔEC mice. n = 4, data represent mean ± SEM, unpaired t‐test.
  • J
    2‐DG uptake levels in vWAT of control and Rbpj iΔEC mice. n = 5, data represent mean ± SEM, unpaired t‐test.