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. 2020 Mar 4;12(4):e11101. doi: 10.15252/emmm.201911101

Figure EV1. USP28 and ΔNp63 mRNA and protein expression in public datasets, TMA and patient material.

Figure EV1

  • A
    Analysis of occurring genetic alterations in USP28 and TP63 in lung cancer (CBioPortal).
  • B
    USP28 and TP63 gene expression heatmap in ADC (n = 364) and SCC (n = 527) lung cancer samples (Xena UCSC software).
  • C
    Representative IHC grading scores of endogenous USP28 and ΔNp63 in lung tissue samples (left panel, low magnification, scale bar 200 μm; right panel high magnification, scale bar 50 μm).
  • D
    Genetic alterations of USP28 in human lung SCC. Each column represents a tumour sample (n = 179 LSCC). Disease‐free survival of USP28 mutant lung SCC patients. Data from TCGA were analysed using cBioPortal software.