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. 2020 Apr 6;20:284. doi: 10.1186/s12885-020-06789-2

Table 3.

Five-year survival rates among testicular cancer patients from different racial groups, stratified by age, marital status, stage at diagnosis, location, and treatment

Survival rates Total NHW HW Black API P-value
All ages 94.4 95.0 92.3 88.8 91.7
(94.1–94.6) (94.7–95.3) (91.5–93.0) (86.6–90.6) (89.9–93.1)
 0–39 94.4 95.2 92.1. 88.9 92.2 0.003
(94.1–94.7) (94.9–95.5) (91.2–92.8) (86.3–91.1) (90.3–93.7)
 40–64 94.9 95.3 93.8 88.9 92.3 0.012
(94.4–95.4) (94.7–95.8) (91.6–95.4) (84.2–92.3) (88.3–94.9)
 65+ 82.8 84.1 79.0 46.9 65.6 0.008
(77.4–87.1) (78.2–88.5) (57.5–90.5) (12.7–75.7) (41.9–81.6)
Marital status
 Single 92.1 92.9 90.3 86.2 90.0 < 0.001
(91.7–92.5) (92.4–93.4) (89.2–91.4) (83.0–88.8) (87.4–92.0)
 Married 96.7 97.0 95.6 92.4 93.5 < 0.001
(96.4–97.0) (96.7–97.4) (94.5–96.5) (88.7–94.9) (90.9–95.4)
 Separated/D/W 90.3 90.8 865 87.8 91.8 0.221
(88.8–91.6) (89.2–92.2) (81.3–90.3) (76.8–93.8) (80.3–96.7)
Stage at diagnosis
 Localized 98.7 98.9 98.2 97.1 97.8 0.002
(98.5–98.9) (98.6–99.1) (97.5–98.7) (94.9–98.3) (96.2–98.7)
 Regional 94.9 95.3 94.5 87.7 91.0 0.009
(94.3–95.4) (94.6–95.9) (92.8–95.8) (82.0–91.7) (86.3–94.1)
 Distant 69.6 71.0 67.5 58.4 62.8 < 0.001
(68.2–70.9) (69.4–72.5) (64.3–70.4) (50.6–65.5) (55.2–69.5)
Location
 Undescended 93.4 93.7 92.0 90.7 95.5 < 0.001
 testis (91.1–95.2) (90.7–95.8) (85.2–95.8) (75.9–96.6) (83.8–98.8)
 Descended 95.6 96.8 92.6 91.1 93.1 < 0.001
 testis (95.2–96.0) (96.3–97.2) (91.4–93.6) (86.5–94.2) (89.8–95.3)
 Testis (NOS) 93.8 94.3 92.1 87.8 90.7 < 0.001
(93.5–94.1) (94.0–94.7) (91.0–93.1) (84.9–90.1) (88.5–92.5)
Histologic subtype
 Seminomas 97.9 98.1 97.3 96.4 96.6 < 0.001
(97.6–98.2) (97.8–98.4) (96.5–98.0) (93.9–97.9) (94.7–97.8)
 Teratomas 93.0 93.8 90.8 84.7 90.7 < 0.001
(92.5–93.5) (93.2–94.4) (89.3–92.1) (78.8–89.0) (86.7–93.5)
 ECs 91.2 91.4 90.7 79.2 89.4 < 0.001
(90.4–92.0) (90.5–92.3) (88.2–92.8) (69.0–86.4) (83.3–93.4)
 Non-seminomas 83.8 87.1 74.5 76.1 75.9 < 0.001
(81.2–86.0) (84.1–89.5) (67.8–80.0) (58.5–87.0) (58.4–86.9)
Treatment
 Surgery 97.0 97.2 96.6 91.6 96.7 0.259
(96.5–97.4) (96.6–97.6) (94.6–97.9) (86.2–95.0) (90.2–98.4)
 Chemotherapy 57.2 56.2 68.7 38.2 58.7 < 0.001
(51.8–62.3) (49.8–62.0) (53.1–80.0) (17.4–58.9) (80.8–89.5)
 Radiation 83.9 86.9 66.7 50.3 97.3 < 0.001
(72.5–90.9) (75.0–93.3) (5.4–94.5) (0.6–981.2) (93.5–98.9)
 RS 99.1 99.1 99.5 98.3 98.0 0.007
(98.7–99.4) (98.6–99.4) (97.5–99.9) (93.3–99.6) (95.0–99.2)
 CS 89.5 89.9 89.6 84.4 83.8 0.003
(88.7–90.3) (89.0–90.7) (86.6–92.0) (77.7–89.3) (78.4–88.0)
 CR 36.0 44.9 18.8 40.2 40.7 < 0.001
(22.0–50.1) (26.8–61.4) (1.1–53.7) (5.2–75.5) (19.8–60.8)
 CRS 63.4 65.6 59.5 65.1 43.9 0.946
(58.4–67.9) (60.0–70.6) (43.2–72.6) (37.8–82.8) (19.9–65.7)

Cancers were diagnosed in the period from 1973 to 2010 and followed up to 12/31/2015 using data in the SEER 9 database. Data are estimated rates (95% confidence intervals). ECs: embryonal carcinomas.

NHW non-Hispanic whites, HW Hispanic whites, API Asians and Pacific Islanders, ECs embryonal carcinomas, RS radiotherapy plus surgery, CS chemotherapy plus surgery, CR chemotherapy plus radiotherapy, CRS chemotherapy plus radiotherapy plus surgery