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. 2020 Apr 6;18:157. doi: 10.1186/s12967-020-02319-7

Table 1.

Clinical characteristics of the study population

Characteristics Total Patients survived Patients died P Value
No. of patients N = 2174 N = 1981 N = 193
Age 64.54 ± 10.57 63.96 ± 10.54 70.54 ± 8.83 <0.001
Gender, man, n (%) 1713 (78.79%) 1572 (79.35) 141 (73.06) 0.041
Medical history
 Pre-hypertension, n (%) 1183 (54.64) 1072 (54.31) 111 (58.12) 0.313
 Pre-diabetes mellitus, n (%) 470 (21.72) 412 (20.88) 58 (30.37) 0.002
 Pre-heart failure, n (%) 83 (5.3) 60 (4.3) 23 (12.2) <0.001
 Pre-myocardial infarction, n (%) 379 (23.9) 329 (23.6) 50 (26.3) 0.475
At admission
 HR, beats/min 74.99 ± 26.09 74.51 ± 26.69 79.96 ± 18.05 <0.001
 SBP, mm Hg 130.51 ± 22.1 130.68 ± 21.52 128.79 ± 27.43 0.263
 DBP, mm Hg 76.29 ± 12.8 76.52 ± 12.64 73.88 ± 14.11 <0.001
 LVEF,  % 50.52 ± 24.62 50.55 ± 24.95 50.22 ± 19.41 0.896
Risk assessment
 GRACE risk score 92.95 ± 26.1 91.35 ± 25.64 109.44 ± 25.2 <0.001
 TIMI classification 4.58 ± 2.03 4.39 ± 1.94 5.94 ± 2.20 <0.001
Laboratory values
 Serum creatinine, μmol/L 94.44 ± 51.3 92.69 ± 47.87 112.37 ± 76 <0.001
 Blood glucose, mmol/L 7.17 ± 3.3 7.03 ± 3.11 8.59 ± 4.6 <0.001
 Total cholesterol, mmol/L 4.13 ± 1.11 4.13 ± 1.1 4.09 ± 1.2 0.602
 WBC, n × 109/L 7.92 ± 5.66 7.79 ± 5.75 9.23 ± 4.43 <0.001
 RBC, n × 1012/L 4.45 ± 1.11 4.47 ± 1.15 4.16 ± 0.65 <0.001
 Hemoglobin, g/L 134.22 ± 35.39 135.17 ± 36.42 124.42 ± 19.89 <0.001
 Platelets, n × 109/L 162.28 ± 61.05 161.79 ± 60.75 167.33 ± 63.95 0.229
 AST, U/L 56.91 ± 102.95 52.55 ± 81.82 102.8 ± 222.7 <0.001
 Serum K+, mmol/L 3.96 ± 0.47 3.96 ± 0.45 4 ± 0.62 0.261
 Serum Ca2+, mmol/L 2.32 ± 4.4 2.34 ± 4.61 2.16 ± 0.18 0.619
 Fibrinogen, g/L 3.83 ± 11.22 3.8 ± 11.46 4.18 ± 8.23 0.679
Discharge medications
 Aspirin, n (%) 2005 (94.18%) 1865 (96.68%) 140 (70.0%) <0.001
 Clopidogrel, n (%) 2002 (94.03%) 1854 (96.11%) 148 (74.0%) <0.001
 ACEI/ARBs, n (%) 1228 (57.73%) 1140 (59.16%) 88 (44.0%) <0.001
 Beta-blockers, n (%) 1434 (67.45%) 1340 (69.57%) 94 (47.0%) <0.001
 Statins, n (%) 1949 (91.55%) 1807 (93.68%) 142 (71.0%) <0.001

Data are expressed as mean ± SD or counts and percentages, as appropriate

HR heart rate, SBP systolic blood pressures, DBP diastolic blood pressure, LVEF left ventricular ejection fraction, GRACE Global Registry of Acute Coronary Events, TIMI thrombolysis in myocardial infarction, WBC white blood cell, RBC red blood cell, AST aspartate transaminase, ACEI angiotensin-converting-enzyme inhibitors, ARB angiotensin II receptor blockers