Table 3.
SNP | Model | Genotype | Case | Control | OR (95% CI) | P value |
---|---|---|---|---|---|---|
rs1049884 | Additive | T/T | 2 | 1 | 1.173 (0.684–2.009) | 0.5619 |
A/T | 37 | 28 | ||||
A/A | 82 | 71 | ||||
Codominant | T/T | 2 | 1 | 1.732 (0.1538–19.5) | 0.6567 | |
A/T | 37 | 28 | 1.144 (0.6376–2.053) | 0.6517 | ||
A/A | 82 | 71 | – | – | ||
Dominant | T/T,A/T | 39 | 29 | 1.164 (0.6545–2.072) | 0.6045 | |
A/A | 82 | 71 | ||||
Recessive | T/T | 2 | 1 | 1.664 (0.1487–18.62) | 0.6795 | |
A/A,A/T | 119 | 99 | ||||
Allele | T | 41 | 30 | 1.156 (0.6918–1.931) | 0.5801 | |
A | 201 | 170 | ||||
rs11550470 | Additive | T/T | 1 | 0 | 1.499 (0.713–3.151) | 0.2857 |
C/T | 19 | 12 | ||||
C/C | 101 | 88 | ||||
Codominant | T/T | 1 | 0 | NA (NA–NA) | NA | |
C/T | 19 | 12 | NA (NA–NA) | NA | ||
C/C | 101 | 88 | – | – | ||
Dominant | T/T,C/T | 20 | 12 | 1.452 (0.6719–3.138) | 0.3427 | |
C/C | 101 | 88 | ||||
Recessive | T/T | 1 | 0 | NA (NA–NA) | NA | |
C/C,C/T | 120 | 100 | ||||
Allele | T | 21 | 12 | 1.489 (0.7135–3.106) | 0.289 | |
C | 221 | 188 | ||||
rs11607 | Additive | T/T | 17 | 23 | 0.7049 (0.4887–1.017) | 0.06143 |
C/T | 50 | 42 | ||||
C/C | 54 | 35 | ||||
Codominant | T/T | 17 | 23 | 0.4791 (0.2246–1.022) | 0.05691 | |
C/T | 50 | 42 | 0.7716 (0.4273–1.393) | 0.3898 | ||
C/C | 54 | 35 | – | – | ||
Dominant | T/T,C/T | 67 | 65 | 0.6681 (0.3873–1.153) | 0.1471 | |
C/C | 54 | 35 | ||||
Recessive | T/T | 17 | 23 | 0.5472(0.2737–1.094) | 0.08804 | |
C/C,C/T | 104 | 77 | ||||
Allele | T | 84 | 88 | 0.6766 (0.4606–0.9941) | 0.04658 | |
C | 158 | 112 | ||||
rs12933523 | Additive | A/A | 2 | 1 | 1.875(0.8935–3.934) | 0.09646 |
G/A | 19 | 8 | ||||
G/G | 100 | 91 | ||||
Codominant | A/A | 2 | 1 | 1.82 (0.1623–20.41) | 0.6273 | |
G/A | 19 | 8 | 2.161 (0.9023–5.177) | 0.08376 | ||
G/G | 100 | 91 | – | – | ||
Dominant | A/A,G/A | 21 | 9 | 2.123 (0.9251–4.874) | 0.0757 | |
G/G | 100 | 91 | ||||
Recessive | A/A | 2 | 1 | 1.664 (0.1487–18.62) | 0.6795 | |
G/G,G/A | 119 | 99 | ||||
Allele | A | 23 | 10 | 1.995(0.9263–4.299) | 0.07766 | |
G | 219 | 190 | ||||
rs2280026 | Additive | C/C | 14 | 7 | 1.044 (0.6981–1.56) | 0.8355 |
T/C | 42 | 42 | ||||
T/T | 65 | 51 | ||||
Codominant | C/C | 14 | 7 | 1.569 (0.5898–4.175) | 0.3668 | |
T/C | 42 | 42 | 0.7846 (0.4467–1.378) | 0.3987 | ||
T/T | 65 | 51 | – | – | ||
Dominant | C/C,T/C | 56 | 49 | 0.8967 (0.5275–1.524) | 0.6871 | |
T/T | 65 | 51 | ||||
Recessive | C/C | 14 | 7 | 1.738 (0.673–4.49) | 0.2534 | |
T/T,T/C | 107 | 93 | ||||
Allele | C | 70 | 56 | 1.047 (0.6908–1.585) | 0.8301 | |
T | 172 | 144 | ||||
rs3743631 | Additive | G/G | 16 | 4 | 1.638 (1.069–2.509) | 0.02341 |
A/G | 55 | 44 | ||||
A/A | 50 | 52 | ||||
Codominant | G/G | 16 | 4 | 4.16 (1.301–13.3) | 0.01623 | |
A/G | 55 | 44 | 1.3 (0.7464–2.264) | 0.354 | ||
A/A | 50 | 52 | – | – | ||
Dominant | G/G,A/G | 71 | 48 | 1.538(0.9021–2.623) | 0.1137 | |
A/A | 50 | 52 | ||||
Recessive | G/G | 16 | 4 | 3.657 (1.181–11.32) | 0.02452 | |
A/A,A/G | 105 | 96 | ||||
Allele | G | 87 | 52 | 1.598 (1.059–2.409) | 0.02542 | |
A | 155 | 148 | ||||
rs907045 | Additive | A/A | 4 | 1 | 1.831 (1.055–3.177) | 0.03147 |
T/A | 38 | 21 | ||||
T/T | 79 | 78 | ||||
Codominant | A/A | 4 | 1 | 3.949 (0.4317–36.13) | 0.2239 | |
T/A | 38 | 21 | 1.787 (0.963–3.314) | 0.06569 | ||
T/T | 79 | 78 | – | – | ||
Dominant | A/A,T/A | 42 | 22 | 1.885 (1.031–3.446) | 0.03945 | |
T/T | 79 | 78 | ||||
Recessive | A/A | 4 | 1 | 3.385 (0.3722–30.78) | 0.279 | |
T/T,T/A | 117 | 99 | ||||
Allele | A | 46 | 23 | 1.806(1.052–3.1) | 0.03196 | |
T | 196 | 177 | ||||
rs9922601 | Additive | A/A | 6 | 6 | 1.099 (0.6956–1.738) | 0.685 |
T/A | 33 | 22 | ||||
T/T | 82 | 72 | ||||
Codominant | A/A | 6 | 6 | 0.878 (0.2712–2.843) | 0.8283 | |
T/A | 33 | 22 | 1.317 (0.7046–2.462) | 0.3881 | ||
T/T | 82 | 72 | – | – | ||
Dominant | A/A,T/A | 39 | 28 | 1.223 (0.6851–2.183) | 0.496 | |
T/T | 82 | 72 | ||||
Recessive | A/A | 6 | 6 | 0.8174 (0.2552–2.618) | 0.7342 | |
T/T,T/A | 115 | 94 | ||||
Allele | A | 45 | 34 | 1.115 (0.6826–1.822) | 0.6632 | |
T | 197 | 166 |
SNP single nucleotide polymorphisms, OR odds ratio, CI confidence interval