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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Matrix Biol. 2019 Oct 23;85-86:47–67. doi: 10.1016/j.matbio.2019.10.001

Figure 2.

Figure 2

Impact of collagen III reduction on the whole tissue modulus of a) articular cartilage and b) meniscus, as measured by AFM-nanoindentation using microspherical tips (R ≈ 5 μm) in PBS (mean ± 95% CI, n ≥ 5). Each data point represented the average modulus of ≥ 10 indentation locations from one animal. Different letters indicated significant age-dependent differences within the same genotype, p < 0.05. *: p < 0.01 between untreated and chondroitinase ABC (C’ABC)-treated groups within the same genotype at 2-month age.