Impact of collagen III reduction on the subchondral bone structure. a) Representative frontal plane of μCT image (L: lateral, M: medial). b,c) Comparison of subchondral bone structural parameters between 2-month-old wild-type (+/+) and Col3a1+/– (+/−) mice, including b) Subchondral bone plate thickness (SBP Th.), and c) Subchondral trabecular bone (STB) structural characteristics, including bone volume fraction (BV/TV), trabecular number (Tb.N), trabecular thickness (Tb.Th) and trabecular separation (Tb.Sp). No significant difference was detected between the two genotypes (mean ± SD, n = 5). Each data point represents the average value measured from one animal.