Table 3.
Univariate analysis of the study parameters that had a positive role for liver fibrosis. Only those that achieved statistical significance are presented
| Parameter | Effect estimate a | 95% CI | P value |
|---|---|---|---|
| Age (years) | 0.023 | 0.0018–0.067 | 0.0285 |
| AST (IU/ml) | 0.083 | 0.020–0.17 | 0.0003 |
| ALT (IU/ml) | 0.034 | 0.0005–0.114 | 0.0081 |
| γGT (IU/ml) | 0.051 | 0.0057–0.13 | 0.0012 |
| LRE (Yes vs. No) | 4.6 | 1.5–14.3 | 0.0051 |
| Number of LREs | 0.038 | 0.0007–0.114 | 0.0052 |
| Events of transaminasemia | 0.060 | 0.0043–0.16 | 0.0042 |
| HCV co-infection (Yes vs. No) | 4.2 | 1.2–15.1 | 0.0178 |
| Alcohol overuse (Yes vs. No) | 3.9 | 1.1–13.9 | 0.0244 |
| Diabetes Mellitus (Yes vs. No) | 5.6 | 1.0–31.9 | 0.0307 |
| Clinical AIDS (Stage CDC – C vs. non C) | 4.4 | 1.4–13.4 | 0.0055 |
AST Aspartate Aminotransferase, ALT Alanine Aminotransferase γ-GT: Gamma Glutamyl Transpeptidase, LRE Liver related event, HCV Hepatitis C, AIDS Acquired Immune Deficiency Syndrome.
a Effect is reported as epsilon-square (ε2) and odds ratio for the arithmetic and categorical quantities respectively