Fig. 1.

a Schematic overview of EPIGENE framework. b An example of EPIGENE prediction. EPIGENE predictions of METTL4 and NC80 gene show an enrichment of H3K27ac and H3K4me3 at TSS (tracks shown in light violet), H3K36me3 in gene body (tracks shown in green), enhancer mark H3K4me1 few bps upstream or downstream of TSS (tracks shown in pink), RNA Polymerase II in TSS and gene body (tracks shown in blue). The predictions also show an absence of repression marks H3K27me3 and H3K9me3 (tracks shown in black). The corresponding RNA-seq evidence in this genomic region can be seen in the lower-most track (track shown in dark pink)