Table 3.

PHA production by haloarchaea using various substrates

Microorganism	Carbon source	PHA type	PHA production	Fermentation operation mode	References
Har. hispanica	Glucose	P(3HB-co-3.18 mol% 3HV)	Content of 12.26% (wt)	Shake flasks	[105]
Har. marismortui	100% pre-treated vinasse	PHB	Content of 30% (wt); yield of 0.77 g/g; productivity of 0.02 g/L/h	Shake flasks	[69]
Hfx. mediterranei	Glucose	P(3HB-co-12.4 mol% 3HV)	Content of 16.4% (wt)	Shake flasks	[35]
Hfx. mediterranei	Extruded starch	P(3HB-co-10.4 mol% 3HV)	Content of 50.8% (wt)	Fed-batch	[85]
Hfx. mediterranei	25% pre-treated vinasse	P(3HB-co-12.36 mol% 3HV)	Content of 70% (wt); yield of 0.87 g/g; productivity of 0.21 g/L/h	Shake flasks	[61]
Hfx. mediterranei	50% pre-treated vinasse	P(3HB-co-14.09 mol% 3HV)	Content of 66% (wt); yield of 0.52 g/g; productivity of 0.18 g/L/h	Shake flasks	[61]
Hfx. mediterranei	Olive mill wastewater	P(3HB-co-6.5 mol% 3HV)	Content of 43% (wt)	Shake flasks	[62]
Hfx. mediterranei	Enzymatic hydrolysate of cheese whey	P(3HB-co-6 mol% 3HV)	Content of 72.8% (wt), yield of 0.29 g/g; productivity of 0.09 g/L/h	42-L bioreactor	[23]
Hfx. mediterranei	Chemical hydrolysate of cheese whey	P(3HB-co-1.5 mol% 3HV)	Content of 53% (wt); yield of 0.78 g/g; productivity of 4.04 g/L/day	2-L bioreactor	[64]
Hfx. mediterranei	Waste stillage	P(3HB-co-15.4 mol% 3HV)	Content of 71% (wt); yield of 0.35 g/g; productivity of 0.17 g/L/h	Shake flasks	[65]
Hfx. mediterranei	Waste stillage	P(3HB-co-17.9 mol% 3HV)	Content of 63% (wt); yield of 0.27 g/g; productivity of 0.14 g/L/h	Plug-flow reactor	[66]
Hfx. mediterranei	Crude glycerol	P(3HB-co-10 mol% 3HV)	Content of 76% (wt); yield of 0.19 g/g; productivity of 0.12 g/L/h	10-L bioreactor	[68]
Hfx. mediterranei	Ulva sp. hydrolysate	P(3HB-co-8 mol% 3HV)	Content of 55% (wt); productivity of 0.035 g/L/h	Duran bottle	[71]
Hfx. mediterranei	Whey sugars, sodium valerate and γ-butyrolactone	P(3HB-co-21.8 mol% 3HV-co-5.1 mo% 4HB)	Content of 87.5% (wt); yield of 0.20 g/g; productivity of 0.14 g/L/h	10-L bioreactor	[23]
Hfx. mediterranei	Crude glycerol phase and γ-butyrolactone	P(3HB-co-10.0 mol% 3HV-co-5.0 mol% 4HB)	Content of 68.5% (wt); yield of 0.16 g/g; productivity of 0.10 g/L/h	10-L bioreactor	[68]
Hgn. amylolyticum	Glucose	P(3HB-co-20.1 mol% 3HV)	Content of 26.1% (wt)	Shake flasks	[46]
Hgn. amylolyticum	Starch	P(3HB-co-18.7 mol% 3HV)	Content of 16.2% (wt)	Shake flasks	[46]
Hgn. amylolyticum	Glycerol	P(3HB-co-19.6 mol% 3HV)	Content of 7.2% (wt)	Shake flasks	[46]
Hgm. borinquense	Sugarcane bagasse hydrolysate	P(3HB-co-13.29 mol% 3HV)	Content of 45.7% (wt); yield of 0.253 g/g; productivity of 0.0113 g/L/h	Shake flasks	[43]
Nnm. ajinwuensis	Glucose	P(3HB-co-13.93 mol% 3HV)	Content of 61.02% (wt); productivity of 0.21 g/L/h	Repeated shake flasks	[45]