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. 2018 Jul 12;85(2):280–289. doi: 10.1093/neuros/nyy268

FIGURE 2.

FIGURE 2.

PD-L1 IHC across 2016 WHO histomolecular subtypes and RISH correlation. A, Representative images of IDH-wildtype (GBIDHWT) and IDH-mutant (GBIDHM) glioblastoma stained with anti-PD-L1 (SP263). B, Stacked bar chart showing PD-L1 IHC distributed across WHO 2016 diagnoses in the NIH cohort (n = 183). C, Overall, PD-L1 staining intensity (not quantified in the current study) was associated with an increase in PD-L1 RISH signals. D, Across the entire cohort (n = 183), quantitative PD-L1 IHC and mRNA showed a significant positive correlation. Scale bar = 100 μm.