Table 1.
Patients characteristics at baseline and 24 months (n = 70)
| Baseline | 24 months | p | |
|---|---|---|---|
| Demography | |||
| Age (years) | 57.8 ± 10.2 | ||
| Males (%) | 44 (63) | ||
| Body mass index (kg/m2) | 26.4 (22.8–31.3) | ||
| Diabetes (%) | 14 (20) | ||
| Smoking (%) | 36 (51.4) | ||
| CKD duration (months) | 25.4 ± 1.3 | ||
| Laboratory | |||
| eGFR (mL/min/1.73m2) | 37.3 (24.8–51.3) | 31.2 (20.3–51) | < 0.001 |
| Proteinuria (g/24 h) | 0.19 (0–0.49) | 0.43 (0–1) | < 0.001 |
| Hemoglobin (g/dL) | 13.3 ± 1.6 | 12.9 ± 4.4 | < 0.001 |
| Total cholesterol (mg/dL) | 183 (161–205) | 158 (131–188) | < 0.001 |
| HDL-cholesterol (mg/dL) | 49 (41–57) | 41 (35–48) | < 0.001 |
| LDL-cholesterol (mg/dL) | 104 (85–119) | 87 (68–106) | 0.001 |
| Triglycerides (mg/dL) | 129 (99–211) | 127 (89–177) | 0.20 |
| Bicarbonate (mmol/L) | 21.9 ± 3.0 | 25.5 ± 3.8 | < 0.001 |
| Phosphate (mg/dL) | 3.7 (3.1–4.0) | 3.4 (3.1–3.8) | 0.04 |
| Ionized calcium (mmol/L) | 1.29 ± 0.06 | 1.32 ± 0.07 | 0.003 |
| Alkaline Phosphatase (U/L) | 79 (63–93) | 70.5 (60.8–94) | 0.17 |
| Intact PTH (pg/mL) | 88 (61–153) | 98 (56.5–171) | 0.63 |
| Tomography | |||
| Trabecular Bone Density (HU) | 202.9 ± 50.5 | 202.5 ± 51 | 0.91 |
| Cortical Bone Density (HU) | 400 ± 89.9 | 404 ± 94.8 | 0.40 |
| Coronary calcium score (AU) | 5.5 (0–283.8) | 7.5 (0–385.3) | < 0.001 |
eGFR Estimated glomerular filtration rate