Table 2.
Association between maternal 27-year DSSI trajectories and CIDI diagnostic assessments at 27-year follow-up (N = 3501)
| CIDI – 27YR diagnostic details | Low trajectory (48%) | Mid trajectory (42%) | High trajectory (10%) | |
|---|---|---|---|---|
| Lifetime ever major depression (N) | 16.7% (1127) | 32.4% (978) | 53.5% (228) |
χ2 = 157.15 p < 0.001 |
| Mean lifetime number episodes (s.d.) | 2.56 (4.79) | 3.74 (6.12) | 8.07 (16.15) |
F = 7.613 p < 0.001 |
| Mean age at first episode years (s.d.) | 30.05 (11.29) | 26.38 (11.94) | 23.91 (11.02) |
F = 4.598 p = 0.011 |
| Mean duration of first episode weeks (s.d.) | 36.29 (72.26) | 36.07 (58.25) | 61.19 (108.71) |
F = 2.463 p = 0.087 |
| Mean time between epi 1 and 2 weeks (s.d.) | 515.52 (566.79) | 398.71 (389.71) | 347.32 (299.17) |
F = 3.443 p = 0.033 |
| Mean number of years of life affected by depression years (s.d.) | 11.87 (12.88) | 9.45 (8.91) | 18.87 (15.34) |
F = 8.811 p < 0.001 |
| Level of impairment (20% most impaired) attributed to depression last 12 months (N) | 0% (10) | 14.3% (84) | 25.7% (70) |
χ2 = 5.72 p = 0.057 |
| Per cent of lifetime meeting DSM-IV criteria for depression (s.d.)* | 3.73 (0.071) | 5.73 (0.098) | 16.62 (0.363) | |
| Significance of difference between trajectory group means | Low v. mid t = 1.45, p = 0.149 |
Mid v. high t = 3.30 p = 0.001 |
High v. low t = 2.74 p = 0.007 |
*
Per cent of lifetime depressed is calculated by multiplying the number of CIDI (DSM-IV) diagnoses of depression by the duration of the first episode (data on duration of subsequent episodes is not always available) and then dividing by the age (in weeks) of each individual respondent. A small number of outliers (impossible scores) have been removed from the calculations.