Table 2. Aqueous humour cytokines level of 18 uveal melanoma patients before and after IPT.
Cytokines | Before IPT |
After IPT |
Pa | ||
Median | Mean±SD | Median | Mean±SD | ||
VEGF-A | 376.3 | 583.7±587.89 | 537.3 | 1094.6±2167.11 | 0.038 |
PLGF | 1.5 | 1.5±1.18 | 2.1 | 4.7±10.10 | 0.026 |
TGF-β1 | 499.6 | 542.6±260.41 | 401.3 | 451.8±308.19 | 0.088 |
IFN-γ | 458.9 | 404.5±206.18 | 353.0 | 364.9±216.79 | 0.468 |
PD-1 | 31.4 | 40.2±38.52 | 28.7 | 30.5±28.69 | 0.298 |
IL-2 | 8.1 | 8.9±6.36 | 8.6 | 9.1±6.06 | 0.899 |
IL-10 | 1.1 | 1.0±0.37 | 1.2 | 1.0±0.52 | 0.686 |
IL-8 | 20.7 | 52.5±66.82 | 22.6 | 47.8±59.75 | 0.742 |
IGF-I | 214.8 | 556.4±775.34 | 200.3 | 673.1±865.93 | 0.389 |
IPT: Iodine-125 plaque therapy; SD: Standard deviation. aWilcoxon signed rank test was used and P-value with exact 2-tailed was shown.
pg/mL