Table 1.
Summary of clinical sign and virus shedding in Gn pigsa
|
Group |
Time |
n |
Diarrheab |
Virus shedding |
||
|---|---|---|---|---|---|---|
|
Pigs with diarrhea (%)* |
Mean duration days (semc)** |
Pigs with virus shedding (%)* |
Mean duration days (sem)** |
|||
|
Mock |
PID1-3 |
5 |
0 |
0 |
0 |
0 |
|
HuNoV |
19 |
11 (58 %)A |
0.9 (0.2)A |
16 (84 %) |
1.5 (0.2)A |
|
|
HGM |
7 |
0 |
0 |
0 |
0 |
|
|
HuNoV+HGM |
11 |
1 (9 %)B |
0.1 (0.1)B |
11 (100 %) |
2.4 (0.2)B |
|
|
Mock |
PID4-10 |
3 |
0 |
0 |
0 |
0 |
|
HuNoV |
9 |
7 (78 %) |
2.0 (0.5)A |
9 (100 %) |
4.9 (0.7)A |
|
|
HGM |
3 |
0 |
0 |
0 |
0 |
|
|
HuNoV+HGM |
6 |
6 (100 %) |
3.8 (0.7)B |
6 (100 %) |
6.8 (0.2)B |
|
a, Gn pigs were inoculated with a HuNoV GII.4 2006b variant 092895 at 6 days of age. Rectal swabs were collected daily after inoculation to determine faecal consistency scores and virus shedding.
b, Faecal consistency was scored as follows: 0, solid; 1, semisolid; 2, pasty; 3, semiliquid; and 4, liquid. Pigs with scores of or over 2 were considered with diarrhea.
c, sem, standard error of the mean.
*Fisher's exact test or **Mann–Whitney test was used for statistical analysis. Groups with significant differences (P<0.05) were indicated with letters A and B.