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. 2019 Nov 12;22(2):366–374. doi: 10.1002/ejhf.1620

Figure 1.

EJHF-1620-FIG-0001-b

Excess rate ratio (ERR) in heart failure by cumulative anthracycline dose. The regression line is the best fitting linear dose–response relationship. This results in an ERR of 1.5% per mg/m2 [95% confidence interval (CI) 0.5–4.1]. Squares indicate point estimates for dose categories (no anthracycline‐based chemotherapy, ≤240 mg/m2 cumulative anthracycline dose, and >240 mg/m2 cumulative anthracycline dose, see Table 2) and are plotted at the mean cumulative anthracycline dose of each category. There was no significant departure from linearity observed. Patients treated with trastuzumab were excluded from this analysis.