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. 2020 Apr 7;2020(4):CD012946. doi: 10.1002/14651858.CD012946.pub2

Gui‐Hong 2018.

Study characteristics
Methods Study design: randomized controlled trial
Study grouping: parallel group
Number randomly assigned: 240 eyes, 120 participants
Exclusions after randomization: not reported
Number analyzed: 240 eyes, 120 participants
Unit of analysis: eye
Losses to follow‐up: not reported
Handling of missing data: not reported
Power calculation: not reported
Study dates: June 2014 to May 2015
Participants Country: China
Overall mean age: 27.2 years (SD 3.2)
Age range: 19 to 44 years
Gender: women 54%, men 46%
Setting: not reported
Equivalence of baseline characteristics: yes
Inclusion criteria: people with myopia
Exclusion criteria: not reported
Interventions Laser for ablation: not reported
Intervention 1
Intervention: LASIK with a microkeratome
Flap dimensions: not reported
Number of people randomized: 120 eyes, 60 participants
Length of follow‐up:
Planned: not reported
Actual: 6 months
Intervention 2
Intervention: LASIK with a femtosecond laser
Flap dimensions: not reported
Number of people randomized: 120 eyes, 60 participants
Length of follow‐up:
Planned: not reported
Actual: 6 months
Outcomes Mean UCVA after surgery
  • Intervals at which outcome assessed: 1 week, and 1 and 6 months

  • Planned follow‐up: not reported

  • Actual follow‐up: 6 months

  • Scale: logMAR

  • Instrument for measurement: not reported


Mean spherical equivalent of the refractive error after surgery
  • Intervals at which outcome assessed: 1 week, and 1 and 6 months

  • Planned follow‐up: not reported

  • Actual follow‐up: 6 months

  • Scale: D

  • Instrument for measurement: not reported

Identification Sponsorship source: not specified
Country: China
Setting: Institute of Ophthalmology
Comments: none
Author's name: Xiao – Hong Gu
Institution: Gu's Eye Hospital
Email: 3235745327@qq. com
Address: Luohe 462000, Henan Province, China
Notes Trial registration number: not reported
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Comment: method of sequence generation not described
Allocation concealment (selection bias) Unclear risk Comment: method of concealment not described
Blinding of participants and personnel (performance bias)
All outcomes Unclear risk Comment: trial did not describe masking participants or trial personnel
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Comment: trial did not describe masking of outcome assessors
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Comment: unclear whether all participants randomized were analyzed
Selective reporting (reporting bias) Unclear risk Comment: no published trial protocol with which to compare
Other bias Low risk Comment: trial appeared free of other sources of bias