Table 1. Laboratory results during hospitalization in a patient with in vivo haemolysis.
| Analyte | Day 1 (ED) | Day 2, afternoon (ICU) | Day 3 | Day 7 | Day 25 | Reference interval |
|---|---|---|---|---|---|---|
| Serum/plasma colour | Dark brown | Yellow | Light yellow | / | / | Light Yellow |
| Haematology tests | ||||||
| Leukocytes (x109/L) | 21.8 | 13.5 | 11.5 | 9.8 | 7.1 | 3.4 - 9.7 |
| Erythrocytes (x1012/L) | 3.76 | 3.50 | 2.98 | 3.27 | 2.94 | 3.86 - 5.08 |
| Haemoglobin (g/L) | 111 | 99 | 82 | 94 | 84 | 119 - 157 |
| Haematocrit (L/L) | 0.310 | 0.280 | 0.240 | 0.270 | 0.240 | 0.356 - 0.470 |
| MCV (fL) | 82 | 79 | 81 | 83 | 83 | 83 - 97 |
| MCH (pg) | 29 | 28 | 28 | 29 | 29 | 27 - 34 |
| MCHC (g/L) | 359 | 357 | 341 | 346 | 346 | 320 - 345 |
| RDW (%) | 14.1 | 14.3 | 14.4 | 15.2 | 13.9 | 9 - 15 |
| MPV (fL) | 8.6 | 8.8 | 9.4 | 8.7 | 8.7 | 6.8 - 10.4 |
| Platelets (x109/L) | 84 | 72 | 62 | 143 | 181 | 158 - 424 |
| Reticulocytes (‰) | / | 22 | / | / | / | 5 - 22 |
| Biochemistry tests | ||||||
| AST (U/L) | 368 | 241 | 49 | 27 | 19 | 8 - 30 |
| ALT (U/L) | 73 | 54 | 31 | 29 | 13 | 10 - 36 |
| CK (U/L) | 238 | / | 52 | 45 | / | < 153 |
| LD (U/L) | 2900 | / | 490 | 252 | 240 | < 240 |
| GGT (U/L) | 46 | / | 32 | / | / | 9 - 35 |
| ALP (U/L) | 141 | / | 61 | / | / | 64 - 153 |
| Glucose (mmol/L) | 6.6 | / | / | / | / | 4.4 - 6.4 |
| Urea (mmol/L) | 15.5 | 24.6 | 13.7 | 20.9 | 11.0 | 2.8 - 8.3 |
| Creatinine (µmol/L) | 188 | 370 | 323 | 588 | 94 | 49 - 90 |
| Total bilirubin (µmol/L) | 133.4 | / | 15.2 | 11.8 | 8.2 | 3 - 20 |
| Direct bilirubin (µmol/L) | 29.8 | / | 3.4 | 2.6 | 1.4 | < 5.0 |
| Amylase (U/L) | 102 | / | / | / | / | 23 - 91 |
| Sodium (mmol/L) | 135 | 132 | 139 | 140 | 133 | 137 - 146 |
| Potassium (mmol/L) | 4.8 | 4.3 | 4.1 | 4.5 | 4.5 | 3.5 - 4.7 |
| Chloride (mmol/L) | 100 | 99 | 101 | 102 | 102 | 97 - 108 |
| CRP (mg/L) | 63.3 | / | 93.3 | 59.6 | 3.6 | 0 - 5.0 |
| Blood gas analysis | ||||||
| pH | 7.394 | / | / | 7.431 | / | 7.350 - 7.450 |
| pCO2 (kPa) | 4.53 | / | / | 5.86 | / | 4.70 - 6.40 |
| pO2 (kPa) | 7.69 | / | / | 14.40 | / | 10.00 - 13.40 |
| BE | - 3 | / | / | 4 | / | - 2 to 3 |
| Standard bicarbonate (mmol/L) | 21 | / | / | 28 | / | 23 - 27 |
| Actual bicarbonate (mmol/L) | 20.3 | / | / | 28.7 | / | 21.0 - 29.0 |
| Total bicarbonate (mmol/L) | 18.7 | / | / | 27.3 | / | 23.0 - 27.0 |
| Oxygen saturation | 0.89 | / | / | 0.99 | / | 0.94 - 0.98 |
| Methaemoglobin (%) | 3 | / | / | / | / | < 5 |
| Specific proteins | ||||||
| Haptoglobin (g/L) (immunonephelometry) | / | 0.32 | / | 1.48 | 2.20 | 0.30 - 2.00 |
| Haptoglobin (g/L) (immunoturbidimetry) | 0.15 | / | / | / | / | 0.63 - 2.73 |
| Immunoglobulin G (g/L) | / | / | 8.58 | / | / | 7.02 - 16.32 |
| Immunoglobulin A (g/L) | / | / | 2.23 | / | / | 0.77 - 3.03 |
| Immunoglobulin M (g/L) | / | / | 0.53 | / | / | 0.58 - 2.41 |
| Complement C3 (g/L) | / | / | 0.61 | / | / | 0.89 - 1.87 |
| Complement C4 (g/L) | / | / | 0.12 | / | / | 0.17 - 0.38 |
| ED - emergency department. ICU - Intensive care unit. / - not determined. | ||||||